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2 179 551

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IPC

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Application

2000116368/04, 2000-06-20

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Start date

2000-06-20

(22)

Actual filing date

2000-06-20

(45)

Published

2002-02-20

(72)

Inventor

Kilin M.T.Kramarenko N.A.Sidorov V.V.Bryljakov P.M.

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'JuObshchestvo S Ogranichennoj Otvetstvennost'Ju Tekhnika, Meditsina"

METHOD OF SYNTHESIS OF 1-PHENYL-2,3-DIMETHYL-4-IODOPYRAZOLONE-5 (IODOANTIPYRINE) Russian patent published in 2002 - IPC

Abstract RU 2179551 C1

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method of synthesis of 1- phenyl-2,3-dimethyl-4-iodopyrazolone-5 (iodoantipyrine) that a medicinal preparation. Invention proposes method of synthesis of iodoantipyrine by oxidative iodination of antipyrine in neutral medium in isopropyl alcohol used as an organic solvent. Use of the proposed method provides to obtain pharmacopoeia preparation of iodoantipyrine with quantitative yield. EFFECT: improved method of synthesis, increased yield, simplified process. 1 ex

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RU 2 179 551 C1

Authors

Kilin M.T.

Kramarenko N.A.

Sidorov V.V.

Bryljakov P.M.

Dates

2002-02-20—Published

2000-06-20—Filed