FIELD: medical-biological investigation methods. SUBSTANCE: invention relates to investigations involving control of urease activity of tissue samplings and body fluids in order to estimate their bacterial loading, in particular by Helicobacter pylori. Urease activity is determined from the value or time of emergence of indication effect of color reaction proceeding on solid sorbent as the result of interaction of acid-base indicator and products of urea-to-ammonia hydrolysis caused by endogenous urease of microorganisms. Ammonia is fixed by solid capillary or grainy sorbent. Method is realized in device allowing performing express analysis of tissue samplings, body fluids, and aerosols. Urea and acid-base indicator are deposited on solid hygroscopic fibrous or grainy microcapillary sorbent in the form of homogenous fine-crystal dispersion. Tissue samplings can also be used for other investigations. EFFECT: increased rapidity of determination. 10 cl, 49 ex
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