FIELD: medicine, pharmacology. SUBSTANCE: composition includes, parts: nonsteroid antiphlogistic sulfonanilide - nimesulide and its salts 1-53, antihistamine second-generation medicinal preparation being the blocking agent of H1-cetirizine receptors 0.3- 3.3, and certain pharmaceutical base and fillers 44-98.5. The composition could be prepared as preparation for injections, local delivery system, suspension for children, capsules or tablets, two-layer tablets, tablets with delayed release of active ingredients, as gel for local application, composition for single intake daily, and as a dosing inhalator. New composition is useful at treating allergic diseases, such as rhinitis, bronchitis, asthma, nettle rash. The combination of nimesulide and cetirizine provides synergistic pharmacological action. EFFECT: higher efficiency. 10 cl, 8 ex, 3 tbl
