MEQUITAZINE FOR TREATING OR PREVENTING PATHOLOGIES INVOLVING H4 HISTAMINE RECEPTORS Russian patent published in 2014 - IPC A61K31/5415 A61P17/00 

Abstract RU 2510273 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is using 10-[(3R)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine, 10-[(3S)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine or 10-[(3R,3S)-1 -azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine or its pharmaceutically acceptable salts for preparing a drug for preventing or treating obstructive bronchopneumopathy characterised by the fact that the drug is presented in the oral form providing an administered dose of 1 mcg/kg to 10 mg/kg, and characterised by the fact that the drug is presented in the form of a solution for oral pulverisation or a powder for inhalation.

EFFECT: invention provides the respiration recovery, specifically respiration rate, and increases an inspiration and expiration flow, reduces an infiltrated neutrophil count and a direct anti-inflammatory effect.

4 cl, 2 dwg, 10 ex

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RU 2 510 273 C2

Authors

Kler T'Erri

Pshibil'Ski Kristof

Tisn-Versal' Zhaki

Kussak Did'E

Dates

2014-03-27Published

2008-12-04Filed