FIELD: medicine, pharmaceutics.
SUBSTANCE: what is presented is using 10-[(3R)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine, 10-[(3S)-1-azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine or 10-[(3R,3S)-1 -azabicyclo[2.2.2]oct-3-ylmethyl]-10H-phenothiazine or its pharmaceutically acceptable salts for preparing a drug for preventing or treating obstructive bronchopneumopathy characterised by the fact that the drug is presented in the oral form providing an administered dose of 1 mcg/kg to 10 mg/kg, and characterised by the fact that the drug is presented in the form of a solution for oral pulverisation or a powder for inhalation.
EFFECT: invention provides the respiration recovery, specifically respiration rate, and increases an inspiration and expiration flow, reduces an infiltrated neutrophil count and a direct anti-inflammatory effect.
4 cl, 2 dwg, 10 ex
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APPLICATION OF 10-[(3R)-1-AZABICYCLO[2,2,2]OCT-3-YLMETHTYL]-10H-PHENOTHIAZINE FOR PREPARING DRUG SELECTIVELY INHIBITING MUSCARINE RECEPTORS M1L, M2 AND M3 | 2007 |
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Authors
Dates
2014-03-27—Published
2008-12-04—Filed