APPLICATION OF 5-ETHYNYLURACIL AS AN ACTIVATOR OF URACIL-REDUCTASE, PHARMACEUTICAL COMPOSITION, METHOD FOR ITS OBTAINING, PHARMACEUTICAL COMPOSITION FOR INCREASING THE ACTION OR DECREASING THE TOXICITY OF 5-FLUOURACIL Russian patent published in 2002 - IPC

FIELD: pharmaceutics. SUBSTANCE: it is suggested a new inactivator of uracil-reductase - 5-ethynyluracil. It enhances the action of 5-fluouracil and is used in treating the cancer. It is, also, suggested to apply pharmaceutical composition based upon 5-ethynyluracil and the method for its obtaining. Pharmaceutical combination is suggested to enhance the action or decrease the toxicity of 5- fluouracil. Such a combination contains separate or mixed components of 5-ethyluracil and 5-fluouracil or its promedicine for simultaneous, separate or successive injection. EFFECT: increased number of activators. 16 cl, 2 dwg, 8 ex, 1 tbl