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2 091 374

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(51)

IPC

(21) (22)

Application

4895583/04, 1991-05-31

(22)

Actual filing date

1991-05-31

(45)

Published

1997-09-27

(72)

Inventor

Majkl Dzhon Lich[Gb]Mal'Kol'M Stjuart Nobbz[Gb]Ramachandran Ijer[Gb]Klajv Leonard Jits[Gb]Filip Alan Skoun[Gb]

(73)

Holder

Dze Vellkam Faundejshn Limited

METHOD OF PREPARING SUBSTITUTED 5-ARYL-PYRIMIDINES Russian patent published in 1997 - IPC

Abstract RU 2091374 C1

FIELD: chemical industry. SUBSTANCE: product: 5-aryl- pyrimidines of formula; or salts thereof wherein R¹-R⁸ are 2,4-diamino-5-(3,5-dichlorophenyl)-6-trifluoromethyl pyrimidine, 2,4-diamino-6-methyl-5-(2,3-trichlorophenyl) pyrimidine. Reagent 1: compound of formula: . Reagent 2: compound of formula: or formula: . Reaction conditions: subsequent removal optically protecting groups with conversion of the resulting products into free base or salt. EFFECT: more efficient preparation method. 8 cl, 1 tbl

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RU 2 091 374 C1

Authors

Majkl Dzhon Lich[Gb]

Mal'Kol'M Stjuart Nobbz[Gb]

Ramachandran Ijer[Gb]

Klajv Leonard Jits[Gb]

Filip Alan Skoun[Gb]

Dates

1997-09-27—Published

1991-05-31—Filed