FIELD: medicine. SUBSTANCE: the polyvalent vaccine composition contains cell-free components of pertussis vaccine, diphtheria toxoid, tetanus toxoid and inactivated poliovirus. The compositions could, also, contain a conjugate of capsuletype polysacharide Haemophilus influenzae of type b and either tetanus or diphtheria toxoid which could be reconstructed out of lyophilized state by other components of this vaccine. Introduction of multi-component vaccine does not lead to lower immunogenicity of any component due to interaction with other components of the vaccine. EFFECT: higher immunogenicity of vaccine. 25 cl, 1 dwg, 11 tbl
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2012 |
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2005 |
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RU2435609C2 |
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- Klejn Majkl
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1995 |
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|
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2006 |
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RU2444374C2 |
