FIELD: medicine, endocrinology, pharmacy. SUBSTANCE: invention relates to pharmaceutical compositions comprising the insulin sensitivity enhancer in combination with other antidiabetic preparations distinguishing by mechanism action from indicated enhancer that can be used for prophylaxis and treatment of patients with diabetes mellitus. Proposed compositions exhibit the more strong inhibitory effect with respect to hyperglycemia. EFFECT: enhanced effectiveness of composition, valuable medicinal property. 33 cl, 2 tbl
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