FIELD: medicine, traumatology. SUBSTANCE: in pre-reactive and early reactive periods of cold trauma one should introduce isothiobamine per os twice daily - in the morning and in the evening for 10 d, after 1-wk-long interval it is necessary to repeat the intake of isothiobamine for 10 d more. The present innovation provides better results and shortened therapy terms in patients with local cold trauma. EFFECT: higher efficiency of therapy. 1 cl, 1 ex, 4 tbl
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