METHOD OF SYNTHESIS OF DERIVATIVES OF SUBSTITUTED 2-NITROGUANIDINE AND METHODS OF SYNTHESIS OF IN- TERMEDIATE COMPOUNDS Russian patent published in 2003 - IPC

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention describes method of synthesis of substituted derivatives of 2-nitroguanidine of the formula: R₂-N(H)-C(=N-NO₂)-N(H)-CH(R₁)-Het and optionally its E/Z- isomers, mixtures of E/Z-isomers and/or tautomers, respectively, as free form or as salts where R₁, R₂, Het and B values are given in the invention claim characterized on that compound of the formula Q-A-Q (IIa) where A, Q have values given in the invention claim and optionally its E/Z-isomers, mixtures of E/Z-isomers and/or tautomers, respectively, as free form or as salts are subjected for hydrolysis in medium where pH value is less 6. Invention proposes also methods of synthesis of intermediate compounds. EFFECT: improved method of synthesis. 8 cl, 27 tbl, 15 ex