2-SUBSTITUTED 4,5-DIARYLIMIDAZOLES, METHOD FOR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2003 - IPC

Abstract RU 2214408 C2

FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to 2-substituted 4,5-diarylimidazoles of the general formula (I) wherein R₁ means 4-pyridyl; R₂ means phenyl, naphtha-1-yl or naphtha-2-yl that can comprise optionally up to 5 substituents taken among halogen atom; R₃ means hydrogen atom; R₄ means pyridyl optionally substituted with halogen atom or amino-group. Invention describes also method for preparing these compounds and pharmaceutical compositions based on thereof. Invention can be used in medicine for treatment of inflammatory and autoimmune diseases. EFFECT: improved preparing method, valuable medicinal properties of compounds and composition. 6 cl, 3 tbl, 20 ex

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RU 2 214 408 C2

Authors

Reves Laslo

Dates

2003-10-20—Published

1998-06-26—Filed