FIELD: organic chemistry, natural compounds, medicine. SUBSTANCE: invention relates to substances showing efficiency against tumors and viruses being their effect enhance that of usual antitumor and antiviral agents and they show also carcinostatic and antiviral effect on different tolerant tumors. The invention relates to a pharmaceutical composition comprising an antitumor or an antiviral substance represented by the formula (I):
where R1 means the base of nucleic acid represented by the definite formula; R2 means hydrogen atom, hydroxyl group or methoxy-group, or its pharmaceutically acceptable salt; Invention relates also to method of synthesis of substance represented by the formula (I) or its pharmaceutically acceptable salt. Method involves culturing cells of the strain NS that is able to produce the substance represented by the formula (I), collection of substance of the formula (I) from cultural fluid and conversion of this substance if necessary to its pharmaceutically acceptable salt. Also, invention discloses cellular strain and method of treatment. Invention provides attenuated adverse effect of substances on normal cells of body. EFFECT: improved method of synthesis, valuable medicinal properties of compounds and composition. 7 cl, 24 dwg
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