FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology, in particular to obtaining a population of central memory T-lymphocytes, and can be used in medicine. A population of cells is obtained, having a central memory T-lymphocyte (Tcm) phenotype and which do not induce anti third party GVHD, wherein at least 50% of the cells have the CD8+, CD62L+, CD45RA-, CD45 RO+ signature.
EFFECT: invention enables to obtain a population of tolerance inducing cells that are capable of homing to lymph nodes after transplantation.
15 cl, 13 dwg, 9 ex
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