FIELD: biotechnology, virology. SUBSTANCE: invention relates to methods for preparing virus-like particles of human papilloma virus (VLP) used in vaccines design. Method involves transformation of yeast cell with DNA molecule encoding L1-HPV (human papilloma virus) or L1 + L2HPV, culturing transformed cells, collection of VLP from transformed cells and purification of VLP by chromatography stage. EFFECT: improved preparing method. 3 cl, 14 dwg, 40 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PAPILLOMA VIRUS PURIFIED PROTEINS | 1995 |
|
RU2161651C2 |
| EXPRESSING VECTOR (VARIANTS) | 1995 |
|
RU2177999C2 |
| POLYNUCLEOTIDE VACCINE FOR PAPILLOMA VIRUS | 1995 |
|
RU2173170C2 |
| OPTIMISED EXPRESSION OF HPV 58 L1 IN YEAST | 2004 |
|
RU2370538C2 |
| OPTIMISED EXPRESSION OF HPV 52 L1 IN YEAST | 2005 |
|
RU2373219C2 |
| NUCLEIC ACID MOLECULE ENCODING HPV 31 L1, EXPRESSION VECTOR, HOST CELL, VIRUS-LIKE PARTICLE AND METHOD OF ITS OBTAINMENT, VACCINE, PHARMACEUTICAL COMPOSITION AND METHODS INVOLVING THEM | 2004 |
|
RU2356943C2 |
| OPTIMISED EXPRESSION LI HPV45 IN YEAST | 2004 |
|
RU2360001C2 |
| POLYPEPTIDES FOR INDUCTION OF PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS | 2004 |
|
RU2337108C2 |
| METHOD OF OBTAINING A RECOMBINANT VACCINE FOR PREVENTION OF HUMANPAPILLOMA VIRUS INFECTION, RECOMBINANT VACCINE | 2018 |
|
RU2681174C1 |
| PICHIA ANGUSTA RECOMBINANT YEAST STRAIN - PRODUCER OF CAPSID PROTEIN L1 OF HUMAN PAPILLOMAVIRUS TYPE 16 | 2011 |
|
RU2445357C1 |
