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2 337 108

(13)

C2

(51)

IPC

C07K14/31(2006-01-01)

A61K39/85(2006-01-01)

C12N15/31(2006-01-01)

C12P21/00(2006-01-01)

(21) (22)

Application

2006105498/13, 2004-07-22

(24)

Start date

2004-07-22

(22)

Actual filing date

2004-07-22

(45)

Published

2008-10-27

(72)

Inventor

Anderson Annaliza S.Jansen Katrin JutKelli RozmariShul'Ts Loren D.Montgomeri Donna L.Makklements Uill'Jam L.

(73)

Holder

Merk Ehnd Ko., Ink.

POLYPEPTIDES FOR INDUCTION OF PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS Russian patent published in 2008 - IPC C07K14/31 A61K39/85 C12N15/31 C12P21/00 

Abstract RU 2337108 C2

FIELD: medicine; pharmacology.

SUBSTANCE: polypeptides under the invention include amino-acid sequence, structurally related sequence SEQ ID NO:1 resulted in the text of the description, to use of such polypeptides as immunogens, including as a part of compositions. The invention opens also expression systems for producing such polypeptides. The sequence SEQ ID NO:1 represents a truncated derivative of full-size polypeptide S. aureus. This full-size polypeptide is designated in the invention as full-size "ORF0657n". It is established, that the polypeptides described in the invention and containing amino-acid sequence are SEQ ID NO:1.

EFFECT: polypeptides cause protective immune response against staphylococcus aureus.

43 cl, 56 dwg, 4 tbl, 17 ex

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RU 2 337 108 C2

Authors

Anderson Annaliza S.

Jansen Katrin Jut

Kelli Rozmari

Shul'Ts Loren D.

Montgomeri Donna L.

Makklements Uill'Jam L.

Dates

2008-10-27—Published

2004-07-22—Filed

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