FIELD: organic chemistry, fungicides, pharmacy. SUBSTANCE: invention relates to pharmaceutical composition comprising the following components: 1) (-)-(2R-cis)-4-[4-[4- [4-[[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazole-1-ylmethyl)furan-3-yl] methoxy]phenyl]-1- piperazinyl]phenyl] -2,4-dihydro-2-(S)-hydroxypropyl] -3H-1,2,4-triazole-3-one as an antifungal agent; 2) at least one nonionic surface-active substance and 3) diluting agent. The composition confers to an antifungal compound with low water-soluble property the enhanced bioavailability in mammals including humans. EFFECT: improved and enhanced properties of composite. 19 cl, 16 tbl
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Authors
Dates
2003-06-27—Published
1997-05-21—Filed