MEDICATION INTENDED FOR PERORAL INTRODUCTION CONTAINING CYCLOOXIGENASE-2 INHIBITOR AND METHOD OF OBTAINING IT Russian patent published in 2010 - IPC A61K31/4164 A61K9/50 A61K9/16 A61K9/22 A61P29/00 

Abstract RU 2391099 C2

FIELD: medicine.

SUBSTANCE: claimed invention relates to field of medicine and pharmacology, namely to obtaining medication for peroral introduction. Claimed medication contains agglomerate of hard particles based on at least one excipient, where said agglomerate contains cyclooxigenase-2 inhibitor, corresponding to compounds of general formula or salts or solvates of such compounds, and at least one hydrophilic polymer, said agglomerate containing product of sputtering on said particles of solution or suspension of finely-grid grains of said inhibitor in said one or several polymers for agglomeration of said particles. Also claimed is method of obtaining said medication. Where R1, R2, R3, X and Y are given in the invention formula.

EFFECT: invention results in obtaining medication for peroral introduction.

28 cl, 1 tbl, 7 ex

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RU 2 391 099 C2

Authors

Moro Marinett

Osti Nikolja

Dates

2010-06-10Published

2006-01-23Filed