FIELD: medicine, hematology, biochemistry, genetic engineering. SUBSTANCE: invention describes sequences of isolated and purified polynucleotides encoding acetyl hydrolase of human plasma platelets activation factor. Invention describes also materials and methods used for recombinant preparing products of acetyl hydrolase of platelets activation factor that are designated for regulation of pathological inflammatory symptoms. EFFECT: expanded assortment of methods and agents used for control of inflammatory diseases. 16 cl, 11 tbl, 13 dwg, 21 ex
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