FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to tetrahydro-gamma-carbolines of the formula (I) 
where R1, R2, D, Alk and n are given in the invention claim. Invention describes also pharmaceutical composition for binding with receptors 5-HT2, 5-HT2a and α2 based on these compounds. Invention provides preparing novel compounds showing valuable biological properties. Invention can be used in medicine. EFFECT: valuable medicinal properties of compounds. 8 cl, 9 tbl, 14 ex
| Title | Year | Author | Number |
|---|---|---|---|
| TRICYCLIC ?3-PIPERIDINES, METHODS FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1999 |
|
RU2230744C2 |
| ANTIBACTERIAL CHINOLIN DERIVATIVES | 2007 |
|
RU2439058C2 |
| DERIVATIVES OF (IMIDAZOL-5-YL)METHYL-2-QUINOLINONE AS INHIBITORS OF SMOOTH MUSCLE CELLS PROLIFERATION | 1998 |
|
RU2209066C2 |
| ANTIBACTERIAL QUINOLINE DERIVATIVES | 2007 |
|
RU2446159C2 |
| BENZOTHIENO[3,2-C]PYRIDINES, METHOD FOR THEIR PREPARING (VARIANTS), PHARMACEUTICAL COMPOSITION AND METHOD FOR ITS PREPARING | 1999 |
|
RU2222542C2 |
| MONOCYCLIC BENZAMIDES OF DERIVATIVES OF 3- OR 4-SUBSTITUTED 4-(AMINOMETHYL)PIPERIDINE, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION, METHOD FOR ITS PREPARING, DERIVATIVE OF CARBOXYLIC ACID | 1998 |
|
RU2213089C2 |
| 1,2,4-TRIAZINE-6-ONE DERIVATIVES, INHIBITING HIV | 2005 |
|
RU2401833C2 |
| DERIVATIVES OF 1,2,3,4-TETRAHYDROBENZOFURO[3,2-C]-PYRIDINE, METHODS OF THEIR SYNTHESIS AND COMPOSITIONS BASED ON THEREOF | 1998 |
|
RU2198175C2 |
| HIV-INHIBITING 5-CARBO- OR HETEROCYCLIC SUBSTITUTED PYRIMIDINES | 2005 |
|
RU2403244C2 |
| DERIVATIVES OF THIADIAZOLYLPYRIDAZINE INHIBITING ANGIOGENESIS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1998 |
|
RU2194049C2 |
