FIELD: medicine, pharmacy. SUBSTANCE: invention proposes a novel agent for treatment or prophylaxis of neointimal thickenings and proliferation and as agent for control or prevention of chronic allograft rejection and pharmaceutical composition based on thereof. Agent represents 40-O-(2- hydroxyethyl)-rapamycin early known as an immunodepressing agent. EFFECT: expanded assortment of agents of claimed designation. 9 cl
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