NEW APPLICATION OF 1,3-PROPANEDIOL DERIVATIVES Russian patent published in 2003 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: application of compound of the formula (I) wherein R means optionally substituted linear or branched carbon chain with 12-22 carbon atoms that can be broken optionally by substituted phenylene; each among R₂, R₃, R₄, R₅ independently each of other means hydrogen atom or lower alkyl in free form or in the form of pharmaceutically acceptable salt for prophylaxis or treatment of chronic rejection of allograft or xenotransplant of organ or tissue in recipient or acute rejection of xenotransplant in recipient. Invention relates to pharmaceutical and therapeutic composition containing these compounds. Invention allows the realization of indicated designation. EFFECT: valuable medicinal properties of derivatives and compositions. 7 cl, 1 ex