FIELD: medical biotechnology. SUBSTANCE: objective of invention is to activate apoptine-induced apoptosis by a variety of agents causing transformation of normal cell or cell disposed to cancer diseases, said apoptine, or so called VP3, being viral protein isolated from chicken anemia virus. Treatment of above-named cells with agents inducing development of tumor will activate apoptine-induced apoptosis leading to death of potentially malignant cells. Agents possessing tumor-generating activity can be examined by their expression in normal cells and their ability to cause apoptine- induced apoptosis. EFFECT: extended choice of agents useful in diagnosis and therapy of tumors. 12 cl, 10 dwg
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