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2 492 238

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(51)

IPC

C12N15/39(2006-01-01)

A61K48/00(2006-01-01)

(21) (22)

Application

2012135656/10, 2012-08-20

(24)

Start date

2012-08-20

(22)

Actual filing date

2012-08-20

(45)

Published

2013-09-10

(72)

Inventor

Chumakov Petr MikhajlovichKochneva Galina VadimovnaBabkina Irina NikolaevnaLupan Tat'Jana Anatol'EvnaGrazhdantseva Antonina Anatol'EvnaJudin Pavel Valer'EvichSivolobova Galina FilippovnaPopov Evgenij Gennad'EvichNetesov Sergej Viktorovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Natsional'Nyj Issledovatel'Skij Gosudarstvennyj Universitet" Gosudarstvennyj Universitet, Ngu)

RECOMBINANT PLASMID DNA pGEM-Puro-DS-Apo COMPRISING SYNTHETIC APOPTIN GENE FLANKED BY SEQUENCES OF VACCINIA VIRUS GENOME OF ISLAND C10L-C12L, AND RECOMBINANT STRAIN VVdGF-ApoS24/2 OF VACCINIA VIRUS PRODUCING APOPTIN Russian patent published in 2013 - IPC C12N15/39 A61K48/00

Abstract RU 2492238 C1

FIELD: biotechnology.

SUBSTANCE: recombinant plasmid DNA pGEM-Puro-DS-Apo is proposed comprising synthetic apoptin gene flanked by sequences of vaccinia virus genome of island C10L-C12L, and the recombinant strain VVdGF-ApoS24/2 of vaccinia virus producing apoptin.

EFFECT: invention can be used to develop medicinal products to control cancerous diseases.

2 cl, 5 dwg, 1 tbl, 6 ex

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RU 2 492 238 C1

Authors

Chumakov Petr Mikhajlovich

Kochneva Galina Vadimovna

Babkina Irina Nikolaevna

Lupan Tat'Jana Anatol'Evna

Grazhdantseva Antonina Anatol'Evna

Judin Pavel Valer'Evich

Sivolobova Galina Filippovna

Popov Evgenij Gennad'Evich

Netesov Sergej Viktorovich

Dates

2013-09-10—Published

2012-08-20—Filed