FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to condensed derivatives of 1,2,4-thiadiazine comprising thiophene and 1,2,4-thiadiazole rings in the system. Invention describes also pharmaceutical composition and for preparing medicine based on these compounds. Compounds show capacity to effect on K+
АТФ
-regulated potassium channels that is useful in treatment of endocrine system, in part, they can be used for reduction of hyperinsulinemia and, therefore, for prophylaxis of diabetes mellitus. EFFECT: improved preparing method, valuable medicinal properties of medicine. 8 cl, 30 ex
| Title |
Year |
Author |
Number |
| DERIVATIVES OF CONDENSED 1,2,4-THIADIAZINE AND CONDENSED 1,4-THIAZINE, THEIR SYNTHESIS AND USING |
1997 |
- Nil'Sen Flemming Ehl'Melunn
- Khansen Khol'Ger Klaus
- Khansen Jokhn Bondo
- Tagmose Tina Meller
|
RU2199542C2 |
| DERIVATIVES OF PYRIDO-1,2,4-THIADIAZINE OR PYRIDO-1,4-THIAZINE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF MANIFESTATION OF ACTIVITY INHIBITING INSULIN SECRETION |
1997 |
- Pirott Bernar
- Lebren Filip
- De Tjull'O Paskal'
- Somer Fabian
- Delarzh Zhak Ehli
- Khansen Khol'Ger Klaus
- Nil'Sen Flemming Ehl'Melunn
- Khansen Jokhn Bondo
|
RU2193564C2 |
| COMPOUNDS AND THEIR USING FOR DECREASING HORMONE-SENSITIVE LIPASE ACTIVITY |
2002 |
- Ehbdrup Seren
- Kornelis De Jong Jokhannes
- Jakobsen Paul'
- Khansen Khol'Ger Klaus
- Vedse Per
|
RU2317981C2 |
| COMPOUNDS AND PHARMACEUTICAL COMPOSITION POSSESSING PROPERTY FOR GROWTH HORMONE RELEASING, METHOD FOR STIMULATION OF SECRETION OF GROWTH HORMONE FROM MAMMAL HYPOPHYSIS |
1999 |
- Peshke Bernd
- Rikhter Shtefan Lutts
- Khansen Tomas Kruse
- Ankersen Mikaehl'
|
RU2298547C2 |
| DERIVATIVES OF PIPERIDINE CARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF, METHOD FOR STIMULATION OF GROWTH HORMONE SECRETION |
1999 |
- Khansen Tomas Kruse
- Ankersen Mikaehl'
|
RU2243215C2 |
| DERIVATIVES OF [1,2,4]-TRIAZOLO-[4,3-A]-QUINOXALINONE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITION OF AMPA- -RECEPTORS |
1995 |
- Nel'Sen Flemming Ehl'Melund
|
RU2149162C1 |
| 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT AND METHODS OF SYNTHESIS |
1993 |
- Kristian Foged
- Rol'F Kholveg
- Ehrik Bardrum Nil'Sen
|
RU2114839C1 |
| ARYLCARBONYL DERIVATIVES AS THERAPEUTIC AGENTS |
2003 |
- Polizetti Dkharma Rao
- Kodra Janos Tibor
- Lau Jesper
- Blok Pav
- Val'Karse-Lopes Marija Karmen
- Blume Nil'S
- Guzel' Mustafa
- Santosh Kalpati Chidambaresvaran
- Mdzhalli Adnan M. M.
- Ehndrjus Robert Karl
- Subramanian Govindan
- Ankersen Mikhael'
- Vedse Per
- Mjurrehj Ehntoni
- Jeppesen Lone
- Lau Jesper
|
RU2340605C2 |
| HETEROCYCLIC COMPOUNDS COMPRISING 2-AMINOPYRIDINE-3-SULFOMIC FRAGMENT, METHODS FOR THEIR PREPARING (VARIANTS), FOCUSED LIBRARY AND PHARMACEUTICAL COMPOSITION |
2004 |
- Dorogov M.V.
- Solov'Ev M.Ju.
- Kravchenko D.V.
- Tkachenko S.E.
- Ivashchenko A.V.
|
RU2263667C1 |
| DERIVATIVES OF 4-ARYL-1-(INDANEMETHYL OR DIHYDROBENZOTHIOPHENE-METHYL)PIPERIDINE, -TETRAHYDROPYRIDINE OR PIPERAZINE AND PHARMACEUTICAL COMPOSITION |
1995 |
- Ens Kristian Perregor
- Jokhn Villi Stenberg
- Bitten Khansen
|
RU2142458C1 |
