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2 216 351

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Application

2002101286/13, 2002-01-22

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Start date

2002-01-22

(22)

Actual filing date

2002-01-22

(45)

Published

2003-11-20

(72)

Inventor

Borisov V.V.Gusev A.A.Surnev D.S.Borisova O.A.Parfenova I.L.Borisov A.V.Smolenskij V.I.

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Vserossijskij Nauchno-Issledovatel'Skij Institut Zashchity Zhivotnykh

INACTIVATED EMULSION VACCINE AGAINST HEN'S HYDROPERICARDITIS SYNDROME (HHPS) Russian patent published in 2003 - IPC

Abstract RU 2216351 C2

FIELD: veterinary virology, biotechnology. SUBSTANCE: the suggested vaccine contains antigenic material as 5-10%-virus-containing suspension out of KR95N114 HHPS virus, inactivating agent as ethylenimine dimer and oily adjuvant in efficient ratio. Strain is deposited in VGNKI collection of microorganisms , registration code being KR95N114 DEP. Strain KR95N114 is reproduced in liver of 5-50-d-aged chickens or in primary hepatic cell culture of SPF-hens' embryos at biological activity of 3,25÷5,0 lg LD50/0,2cu.cm. Vaccine suggested is nonreactogenic, harmless for vaccinated poultry. Moreover, titer of antibodies corresponds to 4,61-4,85 log2. EFFECT: higher efficiency. 8 cl, 11 ex, 9 tbl

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RU 2 216 351 C2

Authors

Borisov V.V.

Gusev A.A.

Surnev D.S.

Borisova O.A.

Parfenova I.L.

Borisov A.V.

Smolenskij V.I.

Dates

2003-11-20—Published

2002-01-22—Filed

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