FIELD: applied biotechnology. SUBSTANCE: for preparing proliposomes method involves mixing phospholipids, organic solvent and filling agent, drying prepared proliposomes, mixing dried proliposomes with solution of biologically active substance in polar solvent and repeated lyophilic drying. Invention provides preparing liposomal preparations based on biologically active substances that loss activity in contact with organic solvents. EFFECT: improved preparing method. 5 cl, 1 tbl, 6 ex
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