METHOD OF PREPARING 1-METHYL-3-ALKYLCYCLOPENTANE-1-OLS Russian patent published in 2003 - IPC

FIELD: organic synthesis. SUBSTANCE: 1-methyl-3-alkylcyclopentane-1-ols of general formula I: (I), wherein R represents n-butyl, n- hexyl, or n-octyl is obtained via reaction of corresponding alpha-olefin with triethylaluminum at molar ratio 10:(1- 14), respectively, in presence of zirconacene dichloride (RCH = CH₂,) taken in amount 3-7 mol % based on alpha-olefin of general formula Cp₂ZrCl₂, wherein R is the same as above - mentioned, reacts in hexane as solvent at room temperature and atmospheric pressure of argon, followed by adding, at temperature -15 C, cuprous chloride catalyst in amount 8-12 mol % based on alpha-olefin and ethyl acetate in equivalent amount to triethylaluminum. Reaction mixture is then stirred at ambient temperature and hydrolyzed. EFFECT: enabled synthesis of 1-methyl-3-alkylcyclopentane-1-ols from accessible reactants under mild conditions. 1 tbl, 11 ex