METHOD FOR COMPLEX EVALUATION OF TUMOR SENSITIVITY TO CHEMOTHERAPY AT MAMMARY GLAND CANCER Russian patent published in 2003 - IPC

Abstract RU 2220418 C2

FIELD: medicine, oncology. SUBSTANCE: the suggested innovation deals with intravenous injection of bromodioxyuridine (BDU) solution 1 h before testing, obtaining tumor part for testing, fixation in formalin solution and evaluation of proliferative activity in preparation after chemotherapy in neoadjuvant mode. At BDU index values being below 8%, Ki-67 being below 24%, alterations in tumor differentiation from low towards higher ones, degree of malignancy from high to low it is useful to conduct chemotherapy by the same scheme; higher BDU and Ki- 67 values, absence of the above-mentioned tendency towards alterations in differentiation and degree of tumor malignancy enable to change chemotherapy scheme prescribed in adjuvant mode. EFFECT: higher accuracy of evaluation and prediction.

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Authors

Semiglazov V.F.

Uporov A.V.

Ivanov V.G.

Topuzov Eh.Eh.

Nurgaziev Kuanesh Kashtybaevich

Bozhok A.A.

Semiglazov V.V.

Paltuev R.M.

Dates

2003-12-27Published

2001-06-27Filed