METHOD FOR CONTROLLING THERAPY WITH INDIRECT ANTICOAGULANTS Russian patent published in 2004 - IPC

FIELD: medicine. SUBSTANCE: indirect anticoagulants are introduced under control of prothrombin time in capillary blood, moreover, prothrombin time is detected by applying thromboplastin standardized by international index of sensitivity and molar ratio of final concentration of anhydrous calcium chloride to final concentration of anhydrous sodium citrate corresponding to 1.5 -2.0 values. Then one should calculate international standardized ratio (ISR) by the following formula: ISR = (PT_patient/PT_control)^IIS, where PT_patient - prothrombin time in patient's capillary blood, PT_control - prothrombin time in capillary blood of healthy persons, IIS - international index of sensitivity of thromboplastin and under ISR one should carry out matching and correcting preparations' dosage, moreover, ISR value should be within 2.0-4.0 limits. EFFECT: higher accuracy of control. 3 ex, 2 tbl