Show metadata Hide metadata

(19)

(11)

2 223 788

(13)

(51)

IPC

(21) (22)

Application

2002103465/15, 1997-03-27

(24)

Start date

1997-03-27

(22)

Actual filing date

1997-03-27

(45)

Published

2004-02-20

(72)

Inventor

Gjuntsburg Val'Ter Kh.Karle PeterZaller Robert Mikhel'

(73)

Holder

Bavarian Nordik Riserch Instit'Jut A/SGsf-Forshungstsentrum Fjur Umvel'T Und Gezundkhajt Gmbkh

CYTOCHROME P-450-TRANSDUCING RETROVIRAL VECTORS Russian patent published in 2004 - IPC

Abstract RU 2223788 C2

FIELD: medicine, oncology, biochemistry, pharmacy. SUBSTANCE: invention relates to medicinal preparations, in particular, retroviral vectors transducing cytochrome P-450. Invention involves pharmaceutical composition for carrying out an anti-tumor therapy and representing capsule, encapsulating cell comprising gene that expresses cytochrome P-450. Capsule comprises porous membrane that is permeable for prodrug molecules that is activated with cytochrome P-450 and converted to an active metabolite. The advantage of invention is the development of new replicatively defective retroviral vectors carrying gene encoding cytochrome P-450. EFFECT: valuable properties of vectors. 7 cl, 5 ex

Similar patents RU2223788C2

Title	Year	Author	Number
RETROVIRAL VECTORS TRANSDUCING CYTOCHROME P450	1997	Gjuntsburg Val'Ter Kh. Karle Peter Zaller Robert Mikhel'	RU2185821C2
CAPSULE FOR CELLS PRODUCING VIRAL PARTICLES, METHOD OF ITS PREPARING AND USING	1996	Zaller Robert Mikhel' Gjuntsburg Val'Ter Kh. Salmons Brajan	RU2187301C2
TREATING OR PREVENTING PROLIFERATIVE CONDITIONS	2010	Everett Stiven Albert Yulkhak Saradzh	RU2705548C2
METHODS AND COMPONENTS FOR INDUCTION OF TUMOR- -SPECIFIC CYTOTOXICITY	1998	Khokhberg Abrakham Ajesh Sukhail	RU2214280C2
COMPOSITION AND METHOD OF TUMOUR CURING	2007	Ogast Pol Khuan Vaan Tszen Natesan Shridaran Liberman Sojan	RU2500815C2
METHODS AND COMPOSITIONS APPLICABLE FOR MODULATION OF ANTIOGENESIS USING PROTEIN KINASES RAF AND RAS	2000	Khud Dzhon Ilajsiri Brajan Cheresh Dehvid A.	RU2257911C2
USE OF COMPOUNDS OF FORMULA A-R-X OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS FOR PREPARING PHARMACEUTICAL COMPOSITION	2007	Mjuller-Ehnokh Diter Khehner Tomas	RU2477275C1
USE OF COMPOUNDS OF FORMULA A-R-X OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS FOR PREPARING PHARMACEUTICAL COMPOSITION	2007	Mjuller-Ehnokh Diter Khehner Tomas	RU2446801C2
MODULATORS OF ANGIOGENESIS AND VESSEL PERMEABILITY	2000	Cheresh Dehvid A. Ehlisejri Brajan Pol Robert	RU2271216C2
PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF DISEASES ASSOCIATED HORMONAL IMBALANCE, INCLUDING RELATED TO P450 CYTOCHROME METABOLIC IMBALANCE	2007	Berdnikova Nadezhda Georgievna Zhilenko Marina Ivanovna Serov Vladimir Nikolaevich Shchelkanova Larisa Anatol'Evna	RU2377984C2

RU 2 223 788 C2

Authors

Gjuntsburg Val'Ter Kh.

Karle Peter

Zaller Robert Mikhel'

Dates

2004-02-20—Published

1997-03-27—Filed