MODULATORS OF ANGIOGENESIS AND VESSEL PERMEABILITY Russian patent published in 2006 - IPC A61K38/17 A61K38/45 A61K48/00 A61P9/10 

Abstract RU 2271216 C2

FIELD: medicine, pharmacology, biochemistry, pharmacy.

SUBSTANCE: invention relates to a pharmaceutical composition and industrial product comprising proteins Src and Yes of tyrosine kinase type together with a pharmaceutically acceptable carrier wherein at least one among protein Src and protein Yes represents active kinase and at least one among protein Scr and protein Yes represents inactive kinase, and to their amino acid sequences also. Invention provides the selective inhibition of tyrosine kinases activity, reduces damages or traumas associated with enhanced permeability of tissue vessels.

EFFECT: valuable medicinal properties of modulators.

16 cl, 16 dwg, 14 ex

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RU 2 271 216 C2

Authors

Cheresh Dehvid A.

Ehlisejri Brajan

Pol Robert

Dates

2006-03-10Published

2000-12-22Filed