POLYPEPTIDE COMPOUND, METHODS FOR ITS PREPARING, PHARMACEUTICAL COMPOSITION AND METHOD FOR PROPHYLAXIS OR TREATMENT OF FUNGAL DISEASES Russian patent published in 2004 - IPC

Abstract RU 2224765 C1

FIELD: organic chemistry, polypeptides. SUBSTANCE: invention relates to polypeptides compound of the general formula (I) wherein R1 means hydrogen atom or acyl group; R2 means hydrogen atom or acyl group; R3 means lower alkyl comprising one or some hydroxyl or protected hydroxyl groups; R4 means hydrogen atom or hydroxy-group; R5 means hydrogen atom, hydroxy-group, lower alkoxy-group or hydroxysulfonyloxy-group; R6 means hydroxy- or acyloxy-group, or its salts. Invention describes also methods for preparing compounds of the formula (I), pharmaceutical composition containing such compounds and method for prophylaxis and/or treatment of fungal diseases also that involves administration of compound of the formula (I). Proposed compounds show anti-fungal activity. EFFECT: improved preparing methods, valuable medicinal properties of compound. 17 cl, 2 tbl, 95 ex

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RU 2 224 765 C1

Authors

Toda Ajako

Matsuja Takakhiro

Mizuno Khiroaki

Matsuda Khirosi

Murano Kendzi

Barrett Dehvid

Ogino Takasi

Matsuda Keidzi

Dates

2004-02-27Published

2001-02-20Filed