FIELD: chemistry.
SUBSTANCE: invention relates to novel sulphonamidethiazole pyrimidine derivatives of formula (I)
, which are glucokinase activators or to their enantiomers, mixture of enantiomers or pharmaceutically acceptable salts. The invention also relates to a pharmaceutical composition based on the novel compounds, use of the compounds to prepare a medicinal agent and to a method of activating glucokinase. In formula (I) R1 denotes (C1-C10)alkoxy, R2 denotes (C3-C6)cycloalkyl, R3 denotes hydrogen, and values of substitutes R4 and R5 are given in the formula of invention.
EFFECT: more effective use of the compounds.
33 cl, 166 ex
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