TRAMADOL-CONTAINING COMPOSITIONS WITH PROLONGED EFFECT THAT ARE ABLE TO RETAIN REQUIRED INDICES FOR RELEASE OF ACTIVE SUBSTANCE IN STORAGE AND METHOD FOR THEIR PREPARING Russian patent published in 2004 - IPC

FIELD: pharmacy. SUBSTANCE: composition containing an active substance is applied with ethylcellulose an aqueous dispersion that comprises as a plasticizer at least one physiologically acceptable lipophilic diester of aliphatic or aromatic dibasic C₆-C₄₀-carboxylic acid and aliphatic C₁-C₈-alcohol. Drying is carried out during applying the coating under usual for this process temperatures. If necessary for increase the rate release of active substance and without deterioration of ability of composition to retain its properties in storage this composition is subjected for thermostatic control at temperature >35 C. Invention provides realization of indicated designation. EFFECT: valuable properties of compositions. 14 cl, 11 dwg, 5 ex