FIELD: medicine.
SUBSTANCE: invention relates to protected against unadministered application peroral medication form with controlled release from it of opioid for single intake per day which is different in that it contains opioid (A), which potentially is a subject of its non-medicinal applicatuion, synthetic or natural polymer (C), which forms retarding opioid release matrix material or retarding opioid release coating, optionally physiologically compatible auxiliary substances (B), optionally wax (D), component (C), respectively component (D) possess resistance to destruction 500 H and component (C) and possibly applied component (D) are present in amounts at which resistance of medication form to destruction constitutes 500 H.
EFFECT: invention also relates to methods of obtaining protected against unadministered application coompositions, which include stages of component mixing, formation by force applicatuion and/or thermal influence and, if necessary, providing retarding opioid release coating.
36 cl, 1 dwg, 1 ex, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| DOSAGE FORM PROTECTED FROM UNINTENDED USE AND CONTAINING (1R, 2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYLPROPYL)PHENOL | 2005 |
|
RU2393847C2 |
| MEDICINAL FORM PROTECTED AGAINST NON-INTENDED USE | 2004 |
|
RU2354357C2 |
| DRUG DOSAGE FORM, PROTECTED FROM UNINTENDED APPLICATION | 2004 |
|
RU2339365C2 |
| PHARMACEUTICAL COMPOSITIONS | 2007 |
|
RU2445077C2 |
| COMPOSITIONS AND METHOD FOR RELIEVING RESPIRATORY DISTRESS CAUSED BY OPIOID OVERDOSE | 2011 |
|
RU2541159C2 |
| CONTROLLED-RELEASE HYDROCODON COMPOSITION | 2001 |
|
RU2253452C2 |
| SYNERGETIC ANALGETIC COMBINATION OF OPIOID ANALGETIC AGENT AND CYCLOOXYGENASE-2 INHIBITOR | 1998 |
|
RU2232600C2 |
| ANALGESIC DRUG WITH SUSTAINED-RELEASING ACTIVE SUBSTANCE | 2000 |
|
RU2244541C2 |
| ABUSE-RESISTANT PHARMACEUTICAL COMPOSITIONS | 2015 |
|
RU2764569C2 |
| FORMULATIONS OF NON-OPIOID AND LIMITED OPIOID ANALGESICS | 2007 |
|
RU2477995C2 |
