FIELD: organic chemistry, medicine, neurology, psychiatry, pharmacology, pharmacy.
SUBSTANCE: invention relates to using compounds 2-arylalkenyl-2-heteroarylalkenyl-, 2-arylalkynyl-, 2-heteroarylalkynyl-, 2-arylazo- and 2-heteroarylazo-, more particularly, 6-methyl-2-(phenylazo)-3-pyridinol, (E)-2-methyl-6-styrylpyridine as antagonists of mGluR 5 receptors used for treatment of pain and fear state by administration of indicated agents in free form, in form of pharmaceutically acceptable salts or as components of pharmaceutical composition.
EFFECT: valuable medicinal properties of antagonists, expanded assortment of medicinal agents.
9 cl
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