FIELD: peptides, medicine, pharmacy.
SUBSTANCE: invention relates to synthetic peptides as antagonists in binding the growth transforming factor TGF-β1 with its receptors in body being this factor shows the sequence comprising from 2 to 15 amino acids that are identical or related with amino acids in the natural the growth transforming factor TGF-β1 and/or its receptors. Peptides can be used as active compounds for preparing compositions used in liver diseases, in particular, in liver fibrosis (cirrhosis).
EFFECT: valuable medicinal properties of peptides.
10 cl, 7 tbl, 28 dwg
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Authors
Dates
2004-07-20—Published
1999-11-23—Filed