USE OF DNA SEQUENCE WHICH CODES PEPTIDE ABLE TO BIND WITH TRANSFORMING GROWTH FACTOR β1 (VERSIONS) Russian patent published in 2012 - IPC C12N15/12 A61K48/00 

Abstract RU 2455358 C2

FIELD: medicine.

SUBSTANCE: invention may be used in medicine. DNA coding a peptide able to bind with TGF-β1 and to inhibit its biological activity in vitro and in vivo is used as an agent inhibiting biological activity of TGF-β1.

EFFECT: invention enables the effective treatment of diseases or pathological disorders associated with hyperexpression or dysregulated expression of TGF-β1 due to inhibition of biological activity of TGF-β1.

4 cl, 6 dwg, 4 tbl, 4 ex

Similar patents RU2455358C2

Title Year Author Number
PEPTIDE CAPABLE OF BINDING WITH β AND INHIBITING BIOLOGICAL ACTIVITY OF β IN VITRO AND/OR IN VIVO, APPLICATION OF PEPTIDE, PHARMACEUTICAL COMPOSITION, DNA SEQUENCE, DNA STRUCTURE, EXPRESSION VECTOR, HOST-CELL AND METHOD OF OBTAINING PEPTIDE 2004
  • Dotor De Las Ehrrerias Khav'Er
  • Lopes Vaskes Ana Belen
  • Lasarte Sagastibel'Sa Khuan Khose
  • Pr'Eto Val'Tuehn'Ja Khesus
  • Borras Kuehsta Fransisko
RU2333917C2
PEPTIDES HAVING CAPACITY TO BIND WITH SCURFIN AND USE THEREOF 2008
  • Kasares Lagar Ines Noehlija
  • Borras Kuehsta Fransisko
  • Sarobe Ugarrisa Pablo
  • Prieto Valtuehn'Ja Khesus
  • Lasarte Sagastibel'Sa Khuan Khose
RU2502741C2
ANTI-GARP-TGF-β-ANTIBODIES 2018
  • Van Der Woning, Sebastian
  • Borgions, Filip
  • Dreier, Torsten
  • Marien, Lore
  • De Boeck, Gitte
  • Lienart, Stephanie
  • Lucas, Sophie
  • Coulie, Pierre
RU2767784C2
INTEGRIN ανβ8 NEUTRALISING ANTIBODIES 2011
  • Nisimura Stiven
  • Lou Tszjan'Lon
  • Baron Dzhodi Linn
  • Marks Dzhejms D.
RU2565539C2
APPLICATION OF INHIBITING TGF-beta1 PEPTIDES FOR PREPARATION OF AGENT MODULATING IMMUNE RESPONSE 2005
  • Borras Kuehsta Fransisko
  • Kasares Agar Noehlia
  • Dotor De Las Ehrrerias Khav'Er
  • Gil Gerrero Lusija
  • Lasarte Sagastibel'Sa Khuan Khose
  • Sarobe Ugarrisa Pablo
  • Pr'Eto Val'Tuehn'Ja Khesus
RU2420307C2
ALPHA-V BETA-8-BINDING ANTIBODIES 2012
  • Nishimura Stiven
  • Lou Tszyanlon
  • Baron Dzhodi Linn
  • Marks Dzhejms
RU2614252C2
INHIBITORS OF SIGNAL TRANSMISSION OF TRANSFORMING GROWTH FACTORS (TGF-R) FOR TREATMENT OF CNS DISORDERS 2005
  • Bogdan Ul'Rikh
  • Ajgner Ljudvig
  • Vaks Frank Peter
  • Vinner Beate
  • Vinkler Jjurgen
RU2385933C2
ANTIBODY OR FRAGMENT THEREOF WITH HIV-NEUTRALISING ACTIVITY 2005
  • Bomsel' Morgan
  • Tudor Daniela
RU2380378C2
CONJUGATES FOR ADMINISTERING BIOLOGICALLY ACTIVE COMPOUNDS 2009
  • Pr'Eto Val'Tuehn'Ja Khesus Marija
  • Berraondo Lopes Pedro
  • F'Oravanti Dzhessika
RU2567667C2
ANTIBODIES SPECIFICALLY BOUND TO EPIDERMAL GROWTH FACTOR RECEPTORS 2009
  • Kim Se-Kho
  • Chang Ki Khvan
  • Khong Kvang-Von
  • Shin Jong-Von
  • Kim Min-Soo
  • Li Khae-Von
  • Shin Jong Nam
  • Rioo Kiung Khvan
  • Seo Dong-Khiuk
RU2518239C2

RU 2 455 358 C2

Authors

Dotor De Las Ehrrerias Khav'Er

Lopes Vaskes Ana Belen

Lasarte Sagastibel'Sa Khuan Khose

Pr'Eto Val'Tuehn'Ja Khesus

Borras Kuehsta Fransisko

Dates

2012-07-10Published

2008-04-21Filed