FIELD: medicine.
SUBSTANCE: invention may be used in medicine. DNA coding a peptide able to bind with TGF-β1 and to inhibit its biological activity in vitro and in vivo is used as an agent inhibiting biological activity of TGF-β1.
EFFECT: invention enables the effective treatment of diseases or pathological disorders associated with hyperexpression or dysregulated expression of TGF-β1 due to inhibition of biological activity of TGF-β1.
4 cl, 6 dwg, 4 tbl, 4 ex
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PEPTIDE CAPABLE OF BINDING WITH β AND INHIBITING BIOLOGICAL ACTIVITY OF β IN VITRO AND/OR IN VIVO, APPLICATION OF PEPTIDE, PHARMACEUTICAL COMPOSITION, DNA SEQUENCE, DNA STRUCTURE, EXPRESSION VECTOR, HOST-CELL AND METHOD OF OBTAINING PEPTIDE | 2004 |
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Authors
Dates
2012-07-10—Published
2008-04-21—Filed