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Application

2003108314/04, 2003-03-25

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Start date

2003-03-25

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Actual filing date

2003-03-25

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Published

2004-07-27

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Inventor

Anisimova V.A.Ponomarev V.V.Galenko-Jaroshevskij A.P.Derlugov L.P.

(73)

Holder

Nauchno-Issledovatel'Skij Institut Fizicheskoj I Organicheskoj Khimii Rostovskogo Gosudarstvennogo UniversitetaGosudarstvennoe Uchrezhdenie Krasnodarskij Nauchnyj Tsentr Ramn I Administratsii Krasnodarskogo Kraja

10-ω-ARYLOXYALKYL-2,3,4,10-TETRAHYDROPYRIMIDO[1,2-A]BENZIMIDAZOLE SALTS ELICITING TOPICALLY ANESTHETIC EFFECT Russian patent published in 2004 - IPC

Abstract RU 2233280 C1

FIELD: organic chemistry, medicine.

SUBSTANCE: invention relates to novel derivatives of 10H-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazole, namely to water-soluble 10-ω-aryloxyalkyl-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazole salts of the general formula:

wherein Ar means C₆H₅, C₆H₄R wherein R means alkoxycarbonyl or carboxy-group at o-, m- and p-position of benzene ring; n = 1-6; X means chlorine (Cl) or bromine (Br) atom. These compounds elicit topically anesthetic effect in infiltration, conduction and intraspinal anesthesia.

EFFECT: valuable medicinal properties of compounds.

2 cl, 4 tbl, 4 ex

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RU 2 233 280 C1

Authors

Anisimova V.A.

Ponomarev V.V.

Galenko-Jaroshevskij A.P.

Derlugov L.P.

Dates

2004-07-27—Published

2003-03-25—Filed