FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to a novel 1,2-disubstituted imidazo[1,2-a]benzimidazole possessing topical anesthetic effect in carrying out infiltration and conduction anesthesia. Invention describes 1-(3-piperidinopropyl)-2-(4-fluorophenyl)imidazo[1,2-a]benzimidazole dihydrochloride of the formula (I): Invention provides synthesis of a novel compound possessing useful biological properties.
EFFECT: valuable medicinal properties of compound.
3 tbl, 1 ex
Title | Year | Author | Number |
---|---|---|---|
1-(3-DIETHYLAMINOPROPYL)-2-(4-FLUOROPHENYL)-IMIDAZO[1,2-a]BENZIMIDAZOLE DIHYDROCHLORIDE ELICITING LOCAL ANESTHETIC EFFECT | 2006 |
|
RU2311416C1 |
AGENT POSSESSING TOPICAL ANESTHETIC EFFECT | 2006 |
|
RU2313341C1 |
1-(2-DIETHYLAMINOETHYL)-2-PHENYLIMIDAZO[1,2-A]BENZIMIDAZOLE DIHYDROCHLORIDE POSSESSING TOPICAL ANESTHETIC EFFECT AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2006 |
|
RU2314312C1 |
1-(3-PYRROLIDINOPROPYL)-2-(4-FLUOROPHENYL)IMIDAZO[1,2-a]-BENZIMIDAZOLE DIHYDROCHLORIDE POSSESSING TOPICAL ANESTHETIZING EFFECT | 2006 |
|
RU2312107C1 |
1-(2-DIETHYLAMINOETHYL)-2-PHENYLIMIDAZO 1,2-a) BENZIMIDAZOLE DIHYDROBROMIDE HAVING LOCALLY ANESTHETIC ACTIVITY | 2000 |
|
RU2160266C1 |
2-TERT-BUTYL-1-(3-CYCLOHEXYL (AMINOPROPYL)IMIDAZO 1,2-A BENZIMIDAZOLE DIHYDROCHLORIDE HAVING LOCALLY ANESTHETIC ACTIVITY | 2000 |
|
RU2160264C1 |
10-ω-ARYLOXYALKYL-2,3,4,10-TETRAHYDROPYRIMIDO[1,2-A]BENZIMIDAZOLE SALTS ELICITING TOPICALLY ANESTHETIC EFFECT | 2003 |
|
RU2233280C1 |
HYDROGEN HALIDES OF N-[2-(1ALKYL-1H-INDOL-3-LY)-1-(4-ALKYLPIPERAZINE-1-CARBONYL)-VINYL]-2-FLUOROBENZAMIDE, HAVING LOCAL ANAESTHETIC AND ANTIARHYTHMIC ACTIVITY | 2008 |
|
RU2408579C2 |
1-(3-PYRROLIDINEPROPYL)-2-PHENYLIMIDAZO 1,2-a) BENZIMIDAZOLE DIHYDROCHLORIDE HAVING LOCALLY ANESTHETIC ACTIVITY | 2000 |
|
RU2160265C1 |
HYDROHALOGENIDES 3-[1-(2-HYDROXY-3-PIPERIDINE-1-YL-PROPYL)-1H-INDOLE-3-YL]-1-PHENYL-PROPENONE, HAVING LOCAL ANAESTHETISING AND ANTI-ARRHYTHMIC ACTIVITY | 2008 |
|
RU2408592C2 |
Authors
Dates
2008-01-10—Published
2006-11-16—Filed