FIELD: medicine, peptides, molecular biology, protein engineering.
SUBSTANCE: invention relates to peptides that can be used for cellular adhesion and healing wounds. The adhesion method involves using recombinant proteins comprising one or more copies of the 2-d and/or the 4-th internal domains βig-h3 with amino acid sequence 237-277 and 498-637, respectively. Invention involves also expressing vectors and strains of E. coli transformed with corresponding expressing vectors. The advantage of invention involves preparing peptides that comprise conservative amino acid sequences that are necessary for activity by attachment, spreading, separation of cells and healing wounds.
EFFECT: valuable method for adhesion and healing.
9 cl, 3 tbl, 23 dwg, 4 ex
