INTEGRIN RECEPTOR ANTAGONISTS AND USE THEREOF Russian patent published in 2020 - IPC A61K51/08 A61P27/02 

Abstract RU 2721907 C2

FIELD: pharmaceuticals; medicine; ophthalmology.

SUBSTANCE: invention is intended for treating macular edema. Pharmaceutical composition for treating macular edema contains an integrin-inhibiting peptide, which consists of Glicinyl-Arginyl-Glycynyl-Cysteic acid-Threonyl-Proline-COOH or a pharmaceutically acceptable salt thereof. In one embodiment, said peptide is a linear peptide and has the structural formula:

EFFECT: use of the invention provides macular edema treatment by inhibiting angiogenesis.

11 cl, 8 tbl, 11 dwg

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RU 2 721 907 C2

Authors

Mackel Michael John

Park John Y.

Karageozian Hampar L.

Karageozian Vicken H.

Dates

2020-05-25Published

2012-05-09Filed