COMBINED THERAPY BY USING ANTIANGIOGENIC AGENTS AND TNF-ALPHA Russian patent published in 2008 - IPC A61K38/19 A61K38/21 A61P35/00

Abstract RU 2316337 C2

FIELD: medicine, combined therapy.

SUBSTANCE: invention relates to pharmaceutical composition for endothelial tumor treatment containing in therapeutically effective amount antiangiogenic agent such as polypeptide including RGD sequence namely cyclo(Arg-Gly-Asp-Dphe-NmeVal) and tumor necrosis factor TNFα. Also disclosed are kit containing pharmaceutical composition, application of abovementioned pharmaceutical composition and kit, and method for therapy.

EFFECT: agent for effective treatment of endothelial tumors.

15 cl, 16 ex, 8 dwg

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RU 2 316 337 C2

Authors

Grell' Mattias

Gudman Sajmon

Rjugg Kurtsio

Dates

2008-02-10—Published

2002-04-18—Filed