NEW APPLICATION OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYLBENZOFURANE-5-YL)-PIPERAZINE AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS Russian patent published in 2004 - IPC

Abstract RU 2237477 C2

FIELD: organic chemistry, medicine, pharmacology.

SUBSTANCE: invention proposes application of 1-[4-(5-cyanoindol)-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)-piperazine and its physiologically acceptable salts as a medicinal preparation for treatment of anxiety disturbance subtype taken among subtypes of panic disturbance coupled or not coupled with the opened space fear, the opened space fear disease, obsessive-maniacal symptomatic disorders, social phobia, post-traumatic stress disorder and/or the general anxiety disturbance. Invention proposes also the application of a pharmaceutical preparation that comprises 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)-piperazine or one of its pharmaceutically acceptable salts as an active component. Indicated application expands the assortment of medicinal agents used in psychiatry.

EFFECT: valuable medicinal properties of agent.

10 cl, 9 ex

Similar patents RU2237477C2

Title Year Author Number
POLYMORPHOUS FORMS OF 1-[4-(5-CYANOINDOLE-3-YL)BUTYL]-4-(2-CARBAMOYLBENOFURAN-5-YL)-PIPERAZINE HYDROCHLORIDE 2002
  • Bate Andreas
  • Khel'Fert Bernd
  • Nojenfel'D Shteffen
  • Knil' Khajke
  • Bartel'S Mattias
  • Rudol'F Zuzanne
  • Bettkher Khenning
RU2303598C2
NEW APPLICATION OF UNITED AGONISTS 5-HT AND INHIBITORS OF SEROTONIN REVERSE CAPTURE 2001
  • Bartoshik Gerd
  • Sedman Juehn
RU2302243C2
NEW USING (R)-(-)-2-[5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMAN AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS 2001
  • Bartoshik Gerd
  • Russ German
  • Zejfrid Kristof
  • Veber Frank
RU2278663C2
USING COMPOUND COMBINING PROPERTY OF SEROTONIN REVERSE UPTAKE INHIBITOR AND AGONIST OF 5-HT-RECEPTOR 2001
  • Gerd Bartoshik
RU2288719C2
NOVEL USING 2-[5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMAN AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS 2002
  • Bartoshik Gerd
  • Russ Germann
  • Zejfrid Kristof
  • Veber Frank
RU2297833C2
COMPOUNDS, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION, SELECTIVE ANTAGONISTS OF 5-HT -RECEPTOR 2001
  • Bettkher Khenning
  • Bartoshik Gerd
  • Kharting Jurgen
  • Van-Amsterdam Kristof
  • Zejfrid Kristof
RU2280034C2
N-(INDOLCARBONYL)PIPERAZINE DERIVATIVES, METHODS FOR PRODUCTION THE SAME, PHARMACEUTICAL COMPOSITION, AND COMPOUNDS 2000
  • Bettkher Khenning
  • Grajner Khartmut
  • Kharting Jurgen
  • Bartoshik Gerd
  • Zejfrid Kristof
  • Van-Amsterdam Kristof
RU2251548C2
DERIVATIVES OF AMIDES AND UREA AS INHIBITORS OF REUPTAKE OF 5-HT AND LIGANDS OF 5-HT1B/1D 1998
  • Mattsen Liza
  • Bettkher Khenning
  • Van-Amsterdam Kristof
  • Bartoshik Gerd
  • Grajner Khartmut
  • Kharting Jurgen
  • Rautenberg Vil'Frid
RU2211216C2
2-4-[4-(4,5-DICHLORO-2-METHYLIMIDAZOLE-1-YL)BUTYL]-1-PIPERAZINYL-5-FLUOROPYRIMIDINE, ITS SYNTHESIS AND THERAPEUTIC USING 1998
  • Merse-Vidal' Ramon
  • Frigola-Konstansa Khordi
RU2191184C2
PARTIAL AGONIST OF DOPAMIN D2/D3 RECEPTORS - 4-{2-[4-(2,3-DICHLOROPHENIL)-PIPERAZIN-1-YL]-ETHYL}-PYPERIDIN-1-CARBONIC ACID METHILAMIDE, METHODS (OPTIONS) OF ITS OBTAINMENT AND APPLICATION 2018
  • Ivashchenko Aleksandr Vasilevich
  • Nikitin Aleksandr Vladimirovich
  • Karapetyan Ruben Navasardovich
  • Kuznetsova Anastasiya Aleksandrovna
RU2677268C1

RU 2 237 477 C2

Authors

Bartoshik Gerd

Zejfrid Kristof

Van-Amsterdam Kristof

Bettkher Khenning

Zedman Ehven

Dates

2004-10-10Published

2000-05-16Filed