NEW APPLICATION OF UNITED AGONISTS 5-HT AND INHIBITORS OF SEROTONIN REVERSE CAPTURE Russian patent published in 2007 - IPC A61K31/496 A61P29/00 A61P1/00 

Abstract RU 2302243 C2

FIELD: medicine.

SUBSTANCE: the present innovation deals with applying compounds being united selective inhibitors of serotonin reverse capture (5-HT) (SSRI) and agonists of 5-HT1a receptor, especially 1-[4-(5-cyanoindole-3-il)butyl]-4-(2-carbamoyl-benzofuran-5-il)-piperazine or its physiologically acceptable salt, or 3-{4-[4-(4-cyanophenyl)-piperazine-1-il]-butyl}- 1H-indole-5-carbonitrile or its physiologically acceptable salt, in particular, hydrochloride, for manufacturing preparation for treating inflammatory bowel syndrome (IBS) The innovation decreases the symptoms of IBS: spastic pains, meteorism, painful constipation or diarrhea.

EFFECT: higher efficiency.

3 cl, 4 ex

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RU 2 302 243 C2

Authors

Bartoshik Gerd

Sedman Juehn

Dates

2007-07-10Published

2001-11-02Filed