USING COMPOUND COMBINING PROPERTY OF SEROTONIN REVERSE UPTAKE INHIBITOR AND AGONIST OF 5-HT-RECEPTOR Russian patent published in 2006 - IPC A61K31/495 A61P25/18 

Abstract RU 2288719 C2

FIELD: organic chemistry, veterinary science.

SUBSTANCE: invention relates ton using a compound combining properties of inhibitor of serotonin (5-HT) reverse uptake and agonist of 5-HT1A-receptors as an agent used in treatment of disorders associated with behavior stressors in veterinary medicine. Indicated compound is chosen from the group consisting of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)-piperazine or its physiologically acceptable salt or 3-{4-[4-(4-cyanophenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile or its physiologically acceptable salt. Invention provides higher level of inhibition of indicated disorders in animals as compared with the known analogues.

EFFECT: improved and valuable medicinal and veterinary properties of compound.

4 cl, 3 ex

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RU 2 288 719 C2

Authors

Gerd Bartoshik

Dates

2006-12-10Published

2001-10-16Filed