FIELD: molecular biology, genetic engineering.
SUBSTANCE: invention concerns characterizing and identifying the gene function using inhibition of double-stranded RNA (dsRNA). Invention proposes a method for incorporation of dsRNA or DNA able for producing dsRNA into C. elegans (variants) and a method for negative regulation of expression of interesting gene in C. elegans (variants). Proposed methods involve incorporation of dsRNA or DNA able for producing dsRNA into C. elegans wherein as result of expression inhibition of expression of target gene occurs. Invention provides carrying out investigations concerning identification of function of target genes and can be used in genetic engineering.
EFFECT: improved method for incorporation, valuable biological properties of gene.
19 dwg, 4 ex
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