METHOD FOR INDIVIDUAL MATCHING PHARMACOTHERAPY IN PATIENTS WITH ACUTE PURULENT OBSTRUCTIVE PYELONEPHRITIS WITH METABOLIC X-SYNDROME Russian patent published in 2004 - IPC

FIELD: medicine, urology.

SUBSTANCE: the present innovation deals with studying clinical and biochemical blood values by the following formula (1):

where A_i - the value of one out of tested parameters; A_min and A_max - the limits for alterations in laboratory values in healthy persons and patients with acute purulent obstructive pyelonephritis followed by calculating the severity coefficient (SC) by the following formula (2):

where I_l - the quantity of leukocytes, I_sn - the quantity of segmented neutrophils, I_rn - the quantity of rod neutrophils, I_u - urea, I_cr - creatinine, I_gl - glucose, I_ac - ACAT. SC value being equal to 2-6 c. u. is considered to be a norm. At SC being below 9 c. u. patients' state is evaluated to be satisfactory followed by performing generally accepted therapy. At SC being above 10 c. u. -the severe state is concluded. Additional therapy with "Immunophan" immunomodulator is required intramuscularly per 1.0 ml daily for 10 d and "Oliphen" antioxidant intravenously per 2 ml of 7%-solution/400 ml isotonic solution twice daily for 10 d, then perorally per 1 tablet thrice daily for 10 d. The innovation enables to correct the course of pharmacotherapy conducted.

EFFECT: higher accuracy of detection.

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