FIELD: pharmaceutical technology, natural compounds.
SUBSTANCE: invention relates to a method for preparing biologically active substances from medicinal vegetable raw, in particular, to preparing pectin substances from wild strawberry leaves (Fragaria vesca L.). Raw is extracted preliminary with hot water at heating to 95oC in the ratio raw : extractant = 1:10 for 1 h to separate water-soluble polysaccharides followed by filtration off. Raw residue is extracted with mixture of 0.5% oxalic acid solution and ammonium oxalate (1:1) in the ratio = 1:20 at 80-85oC for 1 h. The repeated extracted is carried out twice. The vegetable material is separated by filtration and combined extracts are evaporated. Pectin substances are precipitated with 5-fold amount of 96% ethyl alcohol at room temperature. The precipitated dense deposit is filtered off, washed out with 96% ethyl alcohol and dried. Method provides elevating yield of the end product up to 12.5% of vegetable raw mass of wild strawberry leaves.
EFFECT: improved preparing method, expanded source basis of pectin substances.
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Authors
Dates
2005-01-20—Published
2002-12-31—Filed