TRITERPENE COMPOSITIONS AND METHODS FOR THEIR APPLYING Russian patent published in 2005 - IPC

Abstract RU 2244547 C2

FIELD: organic chemistry, natural compounds, medicine, oncology.

SUBSTANCE: invention represents new saponin mixtures used for inhibition of initiation and activation of mammalian epithelial cell in pre-malignant or malignant state, for stimulation of apoptosis of mammalian malignant cell, prophylaxis of anomalous proliferation of mammalian epithelial cell, for treatment of inflammatory and regulation of angiogenesis in mammal. These mixtures are isolated form plants of species Acacia victoriae. Also, invention relates to methods for their applying. These compounds can comprise triterpene component, such as acacic or oleanolic acid to which oligosaccharides and monoterpenoid components are joined. Mixtures and compounds elicit properties associated with regulation of apoptosis and cytotoxicity of cells and strong anti-tumor effect with respect to different tumor cells.

EFFECT: valuable medicinal properties of compositions.

43 cl, 53 tbl, 50 dwg, 44 ex

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RU 2 244 547 C2

Authors

Arntzen Charl'Z Dzh.

Trejsi Mehri Blejk

Gutterman Dzhordan U.

Khoffmann Dzhozef Dzh.

Bejli Dehvid T.

Dzhejatilejk Gamini S.

Dates

2005-01-20Published

1999-05-19Filed